Cufitec™ antiviral and antibacterial technology
Effectiveness and Safety
cufitecEffectiveness and safety of Cufitec™
Cufitec™ has been tested for performance against a variety of microorganisms.
We have confirmed the performance* of various Cufitec™ products and material forms, such as non-woven fabrics, films, and powders, against enveloped viruses (6 types, 23 strains), non-enveloped viruses (3 types, 5 strains), gram-negative bacteria (9 types), and gram-positive bacteria (5 types).
We have also confirmed the various safety features of monovalent copper compound nanoparticles so that our customers can use them with confidence.
*Antiviral and antibacterial performance is judged based on a reduction of 99.9% or more in 1 hour.
Effectiveness of Cufitec™
Virus
Methods
A suspension of monovalent copper compound nanoparticles and a virus solution were mixed to examine the virus infectivity titer after 10 minutes using the plaque method.
*NBC Meshtec's proprietary in-house testing
Results
Enveloped virus (left graph)
The virus infectivity titer was reduced by more than 99.99% in 10 minutes compared to the additive-free solution (detection limit).
Non-enveloped virus (right graph)
The virus infectivity titer was reduced by more than 99.9% in 10 minutes compared to the additive-free solution (detection limit).
Bacteria
Methods
A suspension of monovalent copper compound nanoparticles and a bacterial solution were mixed to examine the viable bacteria count after 10 or 30 minutes using the mixed plate culture method (colony method).
*NBC Meshtec's proprietary in-house testing
Results
Gram-negative bacteria (left graph)
The viable bacteria count was reduced by more than 99.99% in 10 minutes compared to the additive-free solution (detection limit).
Gram-positive bacteria (right graph)
The viable bacteria count was reduced by more than 99.99% in 30 minutes compared to the additive-free solution (detection limit).
Safety of Cufitec™
| Test items | Test results | Testing institution |
|---|---|---|
| Acute oral toxicity test | Minimum lethal dose (LD50 value) > 2,000 mg/kg | Food and Drug Safety Center Hatano Research Institute |
| Ocular irritation test | No irritation of eye tissue (cornea, iris, conjunctiva) | Food and Drug Safety Center Hatano Research Institute |
| Primary skin irritation test | No irritation reaction was found | Food and Drug Safety Center Hatano Research Institute |
| Skin sensitization test | Skin sensitization: Negative | Food and Drug Safety Center Hatano Research Institute |
| Mutagenicity test | Genotoxicity: Negative | Food and Drug Safety Center Hatano Research Institute |
| Cytotoxicity test | Score: 2 (positive= 3 or higher) using a non-woven fabric with Cufitec™ applied | Nelson Laboratories, LLC |
Request for Microbiological Testing
NBC Meshtec has an in-house virus lab and provides microbiological testing for antiviral, antibacterial, anti-biofilm, and other microorganisms. We can flexibly respond to JIS and ISO standard test methods, various specified test standards, and customization of test conditions, etc., to meet your needs.
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If you have any questions or comments about Cufitec®, please feel free to contact us. We will make proposals according to your concerns and wishes regarding microbiological control measures.